Fumonisins are a worldwide major group of fusariotoxins found mainly in corn. Fumonisin B1 is the most frequent fumonisin analogue, with a very high toxicity despite its low absorption in the gut. During food processing, Fumonisin B1 can be hydrolyzed into HFB1 if temperatures are raised above 100°C, leading to chemical degradation via Maillard-type reactions or hydrolysis. The hydrolysis of FB1 into HFB1 can also be caused by specific bacteria encoding type-B carboxylesterase.
In a 2010 survey on wheat in North America, new strains of Fusarium graminearum were isolated and identified as 3-ADON-producing genotypes, though they were not producing any known mycotoxin. In a separate study conducted on rice cultures, it was confirmed that the newly isolated F. graminearum strains were not producing any known mycotoxins. These strains had also been considered for use as biocontrol for DON-producing mold strains.